Severe cutaneous adverse reaction to telaprevir
نویسندگان
چکیده
منابع مشابه
Epidemiology of Severe Cutaneous Adverse Drug Reaction and Its HLA Association among Pediatrics
Severe cutaneous adverse drug reaction (SCAR) is considered to be a multifactorial drug side effect. This study was designed to investigate the epidemiology and human leukocyte antigen (HLA)-A and -B gene polymorphisms in pediatric patients with SCAR admitted in tertiary referral center, southwestern of Iran from 2013 to 2017. Demographic data, past allergy and autoimmune history, clinical pres...
متن کاملEpidemiology of Severe Cutaneous Adverse Drug Reaction and Its HLA Association among Pediatrics
Severe cutaneous adverse drug reaction (SCAR) is considered to be a multifactorial drug side effect. This study was designed to investigate the epidemiology and human leukocyte antigen (HLA)-A and -B gene polymorphisms in pediatric patients with SCAR admitted in tertiary referral center, southwestern of Iran from 2013 to 2017. Demographic data, past allergy and autoimmune history, clinical pres...
متن کاملAnalysis of B cell subsets in severe cutaneous adverse reaction
Background T cells play an important role in the pathogenesis of severe cutaneous adverse reaction (SCAR), while the role of B cell immunity in SCAR is unclear. It has been reported that number of B cell and serum IgG are decreased in the patient’s peripheral blood of drug-induced hypersensitivity syndrome (DIHS) / drug reaction with eosinophilia and systemic symptoms (DRESS) in the acute stage...
متن کاملMultiple drug hypersensitivity associated with severe cutaneous adverse reaction
Background Multiple Drug Hypersensitivity (MDH) was first described by Sullivan et al in 1989 as drug allergies to two or more chemically different drugs proven by in-vivo or in-vitro testing. Pichler et al added to this description by suggesting that there are two subtypes of MDH: one where sensitisation to different drug classes may occur simultaneously; the other, sequentially sometimes even...
متن کاملAllopurinol hypersensitivity syndrome: a preventable severe cutaneous adverse reaction?
INTRODUCTION Allopurinol is a widely-prescribed urate-lowering agent. Allopurinol hypersensitivity syndrome, a severe form of cutaneous adverse reaction, is associated with significant mortality and morbidity. The aim of this study was to document the clinical presentation of allopurinol hypersensitivity in a local population, examine the indications for urate-lowering therapy and to identify p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Dermatology Online Journal
سال: 2015
ISSN: 1087-2108
DOI: 10.5070/d3211025428